A quick search for "rst tmbundle" in Google brought up this TextMate bundle which should work:

https://github.com/textmate/restructuredtext.tmbundle

Is this still a problem for you? I cannot reproduce this anymore on iOS 9.3.2.

Do you see any messages in the Console app when this happens?

This is just a wild guess, but maybe it is trying to open a remote file that it can't reach anymore?

~/Library/Containers/com.textasticapp.textastic-mac/Data/Library/Saved Application State/com.textasticapp.textastic-mac.savedState/

I don't think that's possible with how the system currently works.

I see, thanks for the explanation. That makes it easier for me to build a test scenario.

I'm curious: what do you use the symlinks for in your project?

I can confirm that the stable channel of Firebug Lite does not currently work in Textastic 6 on my iPad.

But, when I open the website https://getfirebug.com/firebuglite in Safari on my Mac, I have the same problem: there is Firebug Lite at the bottom of the screen, but it doesn't respond to mouse clicks.

So it looks to me like this is a bug in the current "stable" version of Firebug Lite.

The good news is: the "debug" channel works! If I use this markup instead, it does work for me:

<script type="text/javascript" src="https://getfirebug.com/firebug-lite-debug.js"></script>